Flubendazole | 31430-15-6
Tlhaloso ea Sehlahisoa:
Flubenzimidazole ke sebolaea-likokoanyana sa benzimidazole se ka thibelang ho monya ha nematode le ho kopanya li-microtubules tsa intracellular.
E ka ba le kamano e matla le tubulin (dimer subunit protheine ea microtubules) le ho thibela li-microtubules ho tloha polymerizing liseleng tsa ho monya (ke hore lisele tsa ho monya liseleng tsa mala a nematode). E ka netefatsoa ke ho nyamela ha (tse ntle) li-microtubules tsa cytoplasmic le ho bokella likaroloana tsa sekhukhu ho cytoplasm ka lebaka la phetisetso e koetsoeng.
Ka lebaka leo, ho roala ha lera la sele ho fetoha mosesaane, 'me matla a ho cheka le ho monya limatlafatsi a fokola. Ka lebaka la ho bokelloa ha lintho tse patiloeng (li-hydrolase le li-enzyme tsa proteolytic), lisele li ba le lysis le ho senyeha, 'me qetellong li lebisa lefung la likokoana-hloko.
Kopo:
Flubenzimidazole ke moriana o lelekang likokoanyana o nang le mefuta e mengata e fapaneng e ka alafang likokoana-hloko lintjang, joalo ka liboko tsa mala, hookworms le whipworms; Ka nako e ts'oanang, e ka boela ea phekola likokoana-hloko tse ngata tsa mala likolobe le likhoho, tse kang Ascaris suum, Hyostrongylus rubidus, Oesophagostomum dentatum, Trichuris suis, Metastrongylus apri, joalo-joalo.
Flubenzimidazole e ke ke ea bolaea batho ba baholo feela empa le mahe.
