Cytidine | 65-46-3

Cytidine ke molek'hule ea nucleoside e entsoeng ka nucleobase cytosine e amanang le ribose ea tsoekere. Ke e 'ngoe ea li-block tsa RNA (ribonucleic acid)' me e phetha karolo ea bohlokoa ho metabolism ea cellular le nucleic acid synthesis.

Sebopeho sa Lik'hemik'hale: Cytidine e na le pyrimidine nucleobase cytosine e kopantsoeng le ribose ea tsoekere e nang le carbon e mehlano ka bond β-N1-glycosidic.

Karolo ea Biological: Cytidine ke karolo ea mantlha ea RNA, moo e sebetsang e le e 'ngoe ea li-nucleosides tse' nè tse sebelisoang kahong ea likhoele tsa RNA nakong ea ho ngoloa. Ntle le karolo ea eona ho motsoako oa RNA, cytidine e boetse e kenya letsoho litseleng tse sa tšoaneng tsa metabolism, ho akarelletsa le biosynthesis ea phospholipids le taolo ea liphatsa tsa lefutso.

Metabolism: Ka hare ho lisele, cytidine e ka ba phosphorylated ho theha cytidine monophosphate (CMP), cytidine diphosphate (CDP), le cytidine triphosphate (CTP), e leng li-intermediate tsa bohlokoa ho nucleic acid biosynthesis le mekhoa e meng ea lik'hemik'hale.

Mehloli ea Lijo: Cytidine e fumanoa ka tlhaho lijong tse ngata, ho kenyelletsa nama, tlhapi, lihlahisoa tsa lebese le meroho e meng. E ka boela ea fumanoa ka lijo ka mokhoa oa cytidine-containing nucleotides le nucleic acids.

Matla a Phekolo: Cytidine le lihlahisoa tsa eona li 'nile tsa batlisisoa bakeng sa mekhoa ea bona ea phekolo e ka' nang ea e-ba teng maemong a fapa-fapaneng a meriana, ho akarelletsa le mafu a methapo ea kutlo, kankere le mafu a bakoang ke kokoana-hloko. Ka mohlala, li-analogue tsa cytidine tse kang cytarabine li sebelisoa chemotherapy ho phekola mefuta e itseng ea leukemia le lymphoma.