Pyridoxal 5'-Phosphate Monohydrate |41468-25-1
Tlhaloso ea Sehlahisoa
Pyridoxal 5'-phosphate monohydrate (PLP monohydrate) ke mofuta o sebetsang oa vithamine B6, e tsejoang hape e le pyridoxal phosphate.
Sebopeho sa Lik'hemik'hale: Pyridoxal 5'-phosphate ke motsoako oa pyridoxine (vithamine B6), e nang le selikalikoe sa pyridine se kopantsoeng le ribose ea tsoekere ea carbon e mehlano, e nang le sehlopha sa phosphate se kopantsoeng le 5' carbon ea ribose.Sebopeho sa monohydrate se bontša boteng ba molek'hule e le 'ngoe ea metsi ka molek'hule ea PLP.
Karolo ea Likokoana-hloko: PLP ke mofuta o sebetsang oa coenzyme oa vithamine B6 'me o sebetsa e le cofactor bakeng sa mefuta e mengata e fapaneng ea liketso tsa enzymatic 'meleng.E bapala karolo ea bohlokoa ho metabolism ea amino acid, neurotransmitter synthesis, le ho qaptjoa ha heme, niacin le nucleic acid.
Liphetoho tsa Enzymatic: PLP e sebetsa joalo ka coenzyme karabelong e mengata ea enzymatic, ho kenyelletsa:
Phetoho ea transamination, e fetisang lihlopha tsa amino lipakeng tsa li-amino acid.
Decarboxylation reactions, e tlosang carbon dioxide ho amino acid.
Racemization le ho felisa karabelo e amehang ho metabolism ea amino acid.
Mesebetsi ea Fisioloji
Amino Acid Metabolism: PLP e ameha metabolism ea amino acid tse kang tryptophan, cysteine, le serine.
Neurotransmitter Synthesis: PLP e kenya letsoho ho qaleng ha li-neurotransmitters tse kang serotonin, dopamine, le gamma-aminobutyric acid (GABA).
Heme Biosynthesis: PLP ea hlokahala bakeng sa ho kopanngoa ha heme, karolo ea bohlokoa ea hemoglobin le cytochromes.
Bohlokoa ba Phepo: Vithamine B6 ke limatlafatsi tsa bohlokoa tse lokelang ho fumanoa lijong.PLP e fumaneha lijong tse fapaneng, ho kenyelletsa nama, tlhapi, likhoho, lijo-thollo, linate le linaoa.
Bohlokoa ba Kliniki: Khaello ea Vithamine B6 e ka lebisa matšoao a methapo, dermatitis, phokolo ea mali, le ts'ebetso ea 'mele ea ho itšireletsa mafung.Ka lehlakoreng le leng, ho ja vithamine B6 ho feteletseng ho ka baka chefo ea methapo.
Sephutheloana
25KG/BAG kapa kamoo o kopang kateng.
Polokelo
Boloka sebakeng se nang le moea oa moea, se omileng.
Maemo a Phethahatso
Maemo a Machaba.
