Huperzine A ｜120786-18-7

Huperzine A ke matlafatso ea kelello e thibelang li-enzyme tse nyenyefatsang acetylcholine ea neurotransmitter ea ho ithuta.Ke ea sehlopha sa limolek'hule tsa cholinergic tse ka thusang ho loantša ho fokotseha ha kelello ho batho ba hōlileng.

Huperzine A ke motsoako o ntšitsoeng lelapeng la huperzine.E bitsoa acetylcholinesterase inhibitor, e bolelang hore e thibela enzyme ho senya acetylcholine, e lebisang ho eketseha ha acetylcholine.

Acetylcholine e bitsoa neurotransmitter ea ho ithuta hape e ameha ho honyeng ha mesifa.

Huperzine A e bonahala e le motsoako o batlang o sireletsehile.Chefo le lithuto tsa batho tse tsoang lithutong tsa liphoofolo ha li bontšitse litla-morao ho litekanyetso tse tloaelehileng tsa tlatsetso.Huperzine A e boetse e sebelisoa litekong tsa pele ho thibela lefu la Alzheimer.

Huperzine A e hlaha ka cerebrospinal fluid mme e tšela habonolo mokoallo oa mali le boko.

Huperzine A e tsebahala haholo e le acetylcholinesterase inhibitor.Haholo-holo, e thibela mofuta oa G4 oa acetylcholinesterase, o tloaelehileng bokong ba mammalian.E sebetsa haholoanyane kapa e sebetsa ka mokhoa o ts'oanang khahlano le li-inhibitors tse ling tsa acetylcholinesterase, joalo ka tacillin kapa rivastatin.Joaloka inhibitor, e na le kamano e phahameng ea acetylcholinesterase.Ka nako e ts'oanang, e na le nako e liehang ea ho arohana, e leng se etsang hore halofo ea bophelo ba eona e be telele haholo.

Ntle le ho thibela acetylcholinesterase, e ka boela ea bonoa e le neuroprotective khahlanong le glutamate, beta amyloid pigmentation, le toxicity e bakoang ke H2O2.

Huperzine A e ka khothalletsa ho ata ha lisele tsa hippocampal neural stem (NSCs).Ho bonahala ho khothalletsa kholo ea methapo ea kutlo ka litekanyetso tse amanang le biorelated.