Uridine | 58-96-8

Uridine ke pyrimidine nucleoside e sebetsang e le motheo oa mohaho oa RNA (ribonucleic acid), e 'ngoe ea mefuta e' meli e meholo ea li-nucleic acid tse hlokahalang bakeng sa ho boloka le ho fetisetsa boitsebiso ba liphatsa tsa lefutso liseleng.

Sebopeho sa Lik'hemik'hale: Uridine e na le pyrimidine base uracil e kopantsoeng le ribose ea tsoekere e nang le carbon e mehlano ka bond β-N1-glycosidic.

Karolo ea Biological:

RNA Building Block: Uridine ke karolo ea bohlokoa ea RNA, moo e etsang mokokotlo oa limolek'hule tsa RNA hammoho le li-nucleoside tse ling tse kang adenosine, guanosine le cytidine.

Messenger RNA (mRNA): Ho mRNA, masala a uridine a kenyelletsa tlhaiso-leseling ea liphatsa tsa lefutso nakong ea ho ngoloa, a nkile litaelo ho tloha ho DNA ho ea mochining oa protheine ka seleng.

Ho fetisa RNA (tRNA): Uridine e boetse e teng limolek'hule tsa intRNA, moo e kopanelang mosebetsing oa ho fetolela ka ho lemoha li-codon tse khethehileng le ho fana ka li-amino acid tse lumellanang le ribosome.

Metabolism: Uridine e ka etsoa ka har'a lisele kapa ea fumanoa mehloling ea lijo. E hlahisoa ka phetoho ea enzymatic ea orotidine monophosphate (OMP) kapa uridine monophosphate (UMP) tseleng ea pyrimidine biosynthesis.

Bohlokoa ba Fisioloji:

Neurotransmitter Precursor: Uridine e bapala karolo ea ts'ebetso ea boko le nts'etsopele. Ke selelekela sa motsoako oa phospholipids ea boko, ho kenyeletsoa phosphatidylcholine, tse bohlokoa bakeng sa botšepehi ba lera la neuronal le pontšo ea li-neurotransmitter.

Liphello tsa Neuroprotective: Uridine e 'nile ea ithutoa bakeng sa thepa ea eona ea ho itšireletsa mafung le bokhoni ba eona ba ho ntlafatsa ts'ebetso ea synaptic le polasetiki ea neuronal.

Matla a Phekolo:

Uridine le lihlahisoa tsa eona li 'nile tsa batlisisoa bakeng sa ts'ebeliso e ka' nang ea e-ba phekolo ea mafu a methapo ea kutlo, ho kenyeletsa lefu la Alzheimer's le mathata a maikutlo.

Tlatsetso ea Uridine e 'nile ea hlahlojoa e le leano la ho tšehetsa ts'ebetso ea kelello le ho fokotsa matšoao a amanang le mafu a neurodegenerative.

Mehloli ea Lijo: Uridine e fumanoa ka tlhaho lijong tse sa tšoaneng, ho akarelletsa nama, tlhapi, meroho le lihlahisoa tsa lebese.