Uridine |58-96-8

Uridine ke pyrimidine nucleoside e sebetsang e le motheo oa mohaho oa RNA (ribonucleic acid), e 'ngoe ea mefuta e' meli e meholo ea li-nucleic acid tse hlokahalang bakeng sa ho boloka le ho fetisetsa boitsebiso ba liphatsa tsa lefutso liseleng.

Sebopeho sa Lik'hemik'hale: Uridine e na le pyrimidine base uracil e kopantsoeng le ribose ea tsoekere e nang le carbon e mehlano ka bond β-N1-glycosidic.

Karolo ea Biological:

RNA Building Block: Uridine ke karolo ea bohlokoa ea RNA, moo e etsang mokokotlo oa limolek'hule tsa RNA hammoho le li-nucleoside tse ling tse kang adenosine, guanosine le cytidine.

Messenger RNA (mRNA): Ho mRNA, masala a uridine a kenyelletsa tlhaiso-leseling ea liphatsa tsa lefutso nakong ea ho ngoloa, a nkile litaelo ho tloha ho DNA ho ea mochining oa protheine ka seleng.

Ho fetisa RNA (tRNA): Uridine e boetse e teng limolek'hule tsa intRNA, moo e kopanelang mosebetsing oa ho fetolela ka ho lemoha li-codon tse khethehileng le ho fana ka li-amino acid tse lumellanang le ribosome.

Metabolism: Uridine e ka etsoa ka har'a lisele kapa ea fumanoa mehloling ea lijo.E hlahisoa ka phetoho ea enzymatic ea orotidine monophosphate (OMP) kapa uridine monophosphate (UMP) tseleng ea pyrimidine biosynthesis.

Bohlokoa ba Fisioloji:

Neurotransmitter Precursor: Uridine e na le karolo ea ts'ebetso ea boko le nts'etsopele.Ke selelekela sa motsoako oa phospholipids ea boko, ho kenyeletsoa phosphatidylcholine, tse bohlokoa bakeng sa botšepehi ba lera la neuronal le pontšo ea li-neurotransmitter.

Liphello tsa Neuroprotective: Uridine e 'nile ea ithutoa bakeng sa thepa ea eona ea ho itšireletsa mafung le bokhoni ba eona ba ho ntlafatsa ts'ebetso ea synaptic le polasetiki ea neuronal.

Matla a Phekolo:

Uridine le lihlahisoa tsa eona li 'nile tsa batlisisoa bakeng sa ts'ebeliso e ka' nang ea e-ba phekolo ea mafu a methapo ea kutlo, ho kenyeletsa lefu la Alzheimer's le mathata a maikutlo.

Tlatsetso ea Uridine e 'nile ea hlahlojoa e le leano la ho tšehetsa ts'ebetso ea kelello le ho fokotsa matšoao a amanang le mafu a neurodegenerative.

Mehloli ea Lijo: Uridine e fumanoa ka tlhaho lijong tse sa tšoaneng, ho akarelletsa nama, tlhapi, meroho le lihlahisoa tsa lebese.