Adenosine 5'-monophosphate | 61-19-8

Adenosine 5'-monophosphate (AMP) ke nucleotide e entsoeng ka adenine, ribose, le sehlopha se le seng sa phosphate.

Sebopeho sa Lik'hemik'hale: AMP e tsoa ho nucleoside adenosine, moo adenine e amahanngoang le ribose, 'me sehlopha sa phosphate se eketsehileng se khomaretsoe ho 5' carbon of ribose ka bond ea phosphoester.

Karolo ea Biological: AMP ke karolo ea bohlokoa ea li-nucleic acid, e sebetsang e le monoma kahong ea limolek'hule tsa RNA. Ho RNA, AMP e kenngoa ka har'a ketane ea polymer ka li-bond tsa phosphodiester, ho etsa mokokotlo oa RNA strand.

Matla a Metabolism: AMP e boetse e ameha ho metabolism ea matla a cellular. E sebetsa e le selelekela sa adenosine diphosphate (ADP) le adenosine triphosphate (ATP) ka karabelo ea phosphorylation e hlahisoang ke li-enzyme tse kang adenylate kinase. ATP, haholo-holo, ke sesebelisoa sa mantlha sa matla liseleng, se fanang ka matla bakeng sa lits'ebetso tse fapaneng tsa cellular.

Taolo ea Metabolic: AMP e bapala karolo ea ho laola tekano ea matla a cellular. Maemo a Cellular AMP a ka fetoha ho latela liphetoho tsa metabolism le litlhoko tsa matla. Maemo a phahameng a AMP a amanang le ATP a ka kenya tšebetsong litsela tse utloang matla a cellular, joalo ka AMP-activated protein kinase (AMPK), e laolang metabolism ho boloka matla a homeostasis.

Mohloli oa Lijo: AMP e ka fumanoa mehloling ea lijo, haholo-holo lijong tse nang le li-nucleic acid, joalo ka nama, tlhapi le linaoa.

Lisebelisoa tsa Pharmacological: AMP le li-derivatives tsa eona li 'nile tsa batlisisoa bakeng sa mekhoa e ka bang teng ea phekolo. Ka mohlala, cAMP (cyclic AMP), e tsoang ho AMP, e sebetsa e le lenģosa la bobeli litseleng tsa ho fetisetsa matšoao 'me e tobisitsoe ke lithethefatsi tse fapa-fapaneng bakeng sa phekolo ea maemo a kang asthma, lefu la pelo le methapo ea mali.